Neonatal lipopolysaccharide exposure induces sexually dimorphic sickness behavior in adult rats.
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چکیده
منابع مشابه
Neonatal lipopolysaccharide exposure induces sexually dimorphic sickness behavior in adult rats
The aim of the present study was to evaluate whether neonatal exposure to lipopolysaccharide (LPS; 50 μg/kg, i.p., on postnatal day 2) induces depressiveand/or anxiety-like effects and sexually dimorphic responses in rats challenged with LPS (100 μg/kg, i.p.) in adulthood. The results revealed that males presented a less depressive state in the forced swim test and exhibited no changes in gener...
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Neuroimmune factors contribute on the pathogenesis of sickness behaviors. Nigella sativa (NS) has anti-inflammatory, anti-anxiety and anti-depressive effects. In the present study, the effect of NS hydro-alcoholic extract on sickness behavior induced by lipopolysaccharide (LPS) was investigated. The rats were divided into five groups (n=10 in each): (1) control (saline), (2) LPS (1 mg/kg, admin...
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ژورنال
عنوان ژورنال: Psychology & Neuroscience
سال: 2014
ISSN: 1983-3288,1984-3054
DOI: 10.3922/j.psns.2014.007